Spheroid Formation of Hepatocarcinoma Cells in Microwells: Experiments and Monte Carlo Simulations

Spheroid Formation of Hepatocarcinoma Cells in Microwells: Experiments and Monte Carlo Simulations

The formation of spherical aggregates during the growth of cell population has long been observed under various conditions. We observed the formation of such aggregates during proliferation of Huh-7.5 cells, a human hepatocarcinoma cell line, in a microfabricated low-adhesion microwell system (SpheroFilm; formed of mass-producible silicone elastomer) on the length scales up to 500 μm. The cell ...

Why Monte Carlo Simulations Are Inferences and Not Experiments

The Use of Monte-Carlo Simulations in Seismic Hazard Analysis in Tehran and Surrounding Areas

Probabilistic seismic hazard analysis is a technique for estimating the annual rate of exceedance of a specified ground motion at a site due to the known and suspected earthquake sources. A Monte-Carlo approach is utilized to estimate the seismic hazard at a site. This method uses numerous resampling of an earthquake catalog to construct synthetic catalogs to evaluate the ground motion hazard a...

Monte Carlo Device Simulations

As semiconductor devices are scaled into nanoscale regime, first velocity saturation starts to limit the carrier mobility due to pronounced intervalley scattering, and when the device dimensions are scaled to 100 nm and below, velocity overshoot starts to dominate the device behavior leading to larger ON-state currents. Alongside with the developments in the semiconductor nanotechnology, in rec...

Monte Carlo simulations.

A description of Monte Carlo methods for simulation of proteins is given. Advantages and disadvantages of the Monte Carlo approach are presented. The theoretical basis for calculating equilibrium properties of biological molecules by the Monte Carlo method is presented. Some of the standard and some of the more recent ways of performing Monte Carlo on proteins are presented. A discussion of the...